Okay, so this probably isn't actually the Ultimate Mix of Life, the Universe, and Everything.
What it is, however, is a cute 2.5D fusion mix with just a little bit of attitude. Shout-out to @TheGentleViking's WesternArtStyle, which helped me achieve this look.
This went well with every checkpoint I tested, but it's particularly gorgeous with SCH Excelsior (see suggested resources for links to that and other checkpoints to try).